Prof. Valentina Prevolnik Rupel, born in 1971 in Ljubljana, holds a PhD from the Faculty of Economics in Ljubljana; her thesis (2008) was entitled "The impact of quality of life on priority setting and the efficiency of resource allocation in healthcare".

In her career, she has worked as a researcher and scientific advisor at the Institute for Economic Research in Ljubljana (IER), where she focused on the fields of health and long-term care. She has been the Chair of the IER Scientific Council, a lecturer at the DOBA Faculty of Applied Business and Social Studies in Maribor, and a member of the Prime Minister's Strategic Council for Health. She has also worked as an advisor to the Minister of Health and counsellor to the Director-General of the Health Insurance Institute of Slovenia.

Her fields of expertise are health outcome measurement and the development of healthcare quality indicators and value-based care, while her broader remit includes healthcare financing and health insurance and health technology assesment.

Before being appointed Minister of Health of the Republic of Slovenia on 13 October 2023, she held the position of the State Secretary at the Ministry of Health.